Detalhe da pesquisa
1.
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.
Cell
; 184(15): 4032-4047.e31, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34171309
2.
Molecular mechanisms by which splice modulator GEX1A inhibits leukaemia development and progression.
Br J Cancer
; 127(2): 223-236, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35422078
3.
Enantioselective Total Synthesis of the Putative Biosynthetic Intermediate Ambruticinâ J.
Chemistry
; 27(43): 11126-11131, 2021 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887073
4.
Conformation-guided analogue design identifies potential antimalarial compounds through inhibition of mitochondrial respiration.
Org Biomol Chem
; 16(30): 5403-5406, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30009295
5.
GEX1A, a Polyketide from Streptomyces chromofuscus, Corrects the Cellular Defects Associated with Niemann-Pick Type C1 in Human Fibroblasts.
J Nat Prod
; 81(9): 2018-2025, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30188717
6.
Synthesis and Biological Evaluation of 7-Deoxy-Epothilone Analogues.
Int J Mol Sci
; 18(3)2017 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28304361
7.
Conformation-activity relationships of polyketide natural products.
Nat Prod Rep
; 32(8): 1183-206, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25974024
8.
Total Synthesis and Structural Reassignment of Lyngbyaloside C Highlighted by Intermolecular Ketene Esterification.
Chemistry
; 21(30): 10681-6, 2015 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26101039
9.
The synthesis and biological evaluation of desepoxyisotedanolide and a comparison with desepoxytedanolide.
Angew Chem Int Ed Engl
; 54(23): 6935-9, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25914374
10.
The marine polyketide myriaporone 3/4 stalls translation by targeting the elongation phase.
Chembiochem
; 14(2): 260-4, 2013 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23303710
11.
Elucidation of gephyronic acid biosynthetic pathway revealed unexpected SAM-dependent methylations.
J Nat Prod
; 76(12): 2269-76, 2013 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24298873
12.
Concise enantioselective synthesis of diospongins A and B.
Tetrahedron
; 69(36): 7706-7712, 2013 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24058215
13.
Strained alkenes in natural product synthesis.
Angew Chem Int Ed Engl
; 52(15): 4078-87, 2013 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23450661
14.
Linear (-)-Zampanolide: Flexibility in Conformation-Activity Relationships.
ChemMedChem
; 18(19): e202300292, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552215
15.
Brain glycogen serves as a critical glucosamine cache required for protein glycosylation.
Cell Metab
; 33(7): 1404-1417.e9, 2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34043942
16.
Application of stereoselective ether transfer to the synthesis of isotactic polyethers.
J Org Chem
; 75(12): 3953-7, 2010 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20481506
17.
Synthesis, conformational preferences, and biological activity of conformational analogues of the microtubule-stabilizing agents, (-)-zampanolide and (-)-dactylolide.
Medchemcomm
; 10(5): 800-805, 2019 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31191870
18.
Electrophile-induced ether transfer: stereoselective synthesis of 2,6-disubstituted-3,4-dihydropyrans.
J Org Chem
; 73(14): 5592-4, 2008 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18570473
19.
Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase.
ACS Chem Biol
; 13(9): 2699-2707, 2018 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30179448
20.
Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria.
PLoS One
; 13(7): e0201605, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30063768